Medicine

Accelerating ASO therapies from development to execution

.Competing enthusiasms.R.S., M.S., H.G. and A.A.R. are actually organizers of the 1M1M initiative. H.G. and A.A.R. are actually board of supervisors participants as well as R.S., M.S. as well as A.A.R. are actually members of the scientific advisory board of N1C. A.A.R. divulges job through LUMC, which possesses patents on exon-skipping innovation, a number of which has been certified to BioMarin and consequently sublicensed to Sarepta. As co-inventor of a few of these licenses, A.A.R. was actually allowed to a reveal of aristocracies. A.A.R. better divulges working as impromptu specialist for PTC Therapies, Sarepta Therapeutics, Regenxbio, Dyne Therapies, Lilly, BioMarin Pharmaceuticals Inc., Eisai, Entrada, Takeda, Splicesense, Galapagos, Sapreme, Italfarmaco and Astra Zeneca. In the past 5 years, A.A.R. likewise performed consulting for Alpha Anomeric. A.A.R. also discloses subscription of the medical boards of advisers of Eisai, Hybridize Rehabs, Silence Rehabs, Sarepta Therapies, Sapreme and Mitorx. Previously 5 years, A.A.R. was also a medical advisory board participant for ProQR. Remuneration for A.A.R. u00e2 s consulting and advising activities is paid to LUMC. In the past 5 years, LUMC additionally got audio speaker honoraria coming from PTC Therapeutics, Alnylam Netherlands, Italfarmaco as well as Pfizer as well as cashing for agreement investigation coming from Sapreme, Eisai, Galapagos, Synaffix and Alpha Anomeric. Project backing is actually acquired from Sarepta Therapeutics as well as Entrada via unregulated gives. H.G. has nothing to divulge in relation to the subjects dealt with in this particular composition. Before 5 years, he has actually likewise gotten consultancy honoraria from UCB. M.S. received consultancy gratuity from Ionis, UCB, Prevail, Orphazyme, Biogen, Servier, Reata, GenOrph, AviadoBio, Biohaven, Zevra, Lilly and Solaxa before 5 years, all unrelated to today document. R.S. has nothing to reveal relative to the subjects dealt with in this document. She has actually gotten sound speaker and/or working as a consultant honoraria or even financing contributions coming from Abbvie, Bial, STADA as well as Everpharma in the past 5 years.

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